Researchers and scientists have long questioned the widespread use of antidepressants. Not only for lack of efficacy, but for the harms associated with them as well. They've also questioned the premise for the prescription of these drugs, mainly the theory that depression is caused by a chemical imbalance in the brain. For decades this theory has permeated the world of health and been accepted as truth despite very little evidence. As a result, antidepressant drugs have become a multibillion dollar industry.